Bupleuri Radix-targeted syndrome, characterized by chest and hypochondrium fullness and discomfort, a bitter taste in the mouth, a dry throat, dizziness, insomnia, anxiety, depression, susceptibility to fright and upset, dreamfulness, and other psychiatric symptoms, along with a red tongue, a thick and yellow tongue coating, and a wiry, hard, and powerful pulse, are among the clinical indications. This formula's utility was discovered to be frequently practiced in concert with additional formulas such as Gualou Xiebai Decoction, Wendan Decoction, Zhizhu Pills, Juzhijiang Decoction, Suanzaoren Decoction, and Banxia Baizhu Tianma Decoction.
A heavy and frequent occurrence of the cardiovascular disease arrhythmia negatively impacts China's public health sector. This ailment plagues an estimated 20 million individuals in China, where pharmacological and surgical treatments are the primary methods of care. Despite their use, antiarrhythmic drugs are known to sometimes induce arrhythmias, and surgical treatments are susceptible to failure and recurrence. Ultimately, enhancing the clinical outcomes associated with arrhythmia remains a significant objective. The traditional Chinese medicine theory of arrhythmia (palpitations) identifies seven contributing factors: liver qi stagnation and depression, accumulation of turbid phlegm, fluids attacking the heart, the heart being disturbed by fire-heat, stasis obstruction of the heart vessels, cold congealing within the heart vessels, and a deficiency in Qi, blood, Yin, and Yang. This research, therefore, articulated seven TCM arrhythmia syndromes, specifically focusing on palpitations related to depression, phlegm, fluid retention, heat, blood stasis, cold, and deficiency. The corresponding treatment strategies, for the palpitation, were advised as follows: Chaihu Longgu Muli Decoction for palpitation associated with depression, Wendan Decoction for phlegm-related palpitation, Linggui Zhugan Decoction for palpitation due to fluid retention, Sanhuang Xiexin Decoction for fire-induced palpitation, Xuefu Zhuyu Decoction for palpitation due to blood stasis, Mahuang Fuzi Xixin Decoction for palpitation caused by cold, and Guizhi Gancao Decoction, Guizhi Gancao Longgu Muli Decoction, Huanglian Ejiao Decoction, Zhigancao Decoction, and Guipi Decoction for palpitation caused by Qi, blood, Yin, or Yang deficiency. Simultaneous TCM syndromes in a patient necessitate the combination of multiple formulas for effective treatment. This research, rooted in the principles of formula-syndrome correlation, integrated considerations of pathogenesis and pathology, and herbal nature and pharmacology, introduced a comprehensive 'pathogenesis-pathology-nature-pharmacology' treatment model to bolster the clinical efficacy of classic herbal formulas in arrhythmia management.
A classic herbal formula, Maxing Shigan Decoction combined with Xiao Chaihu Decoction, embodies the wisdom of traditional medicine. Based on the principles laid down in ZHANG Zhong-jing's Treatise on Cold Damage (Shang Han Lun), each of these statements is formulated. Harmonizing lesser yang, relieving exterior syndrome, clearing lung heat, and relieving panting are consequences of this combination. This treatment method is primarily employed to address illnesses stemming from the triple-Yang combination of diseases, alongside the lung's accumulation of harmful heat. The therapeutic effect of Xiao Chaihu Decoction and Maxing Shigan Decoction is well-recognized in addressing exogenous diseases that affect the triple-Yang. These are widely used in exogenous diseases, especially in the northern part of China. selleck products Coronavirus disease 2019 (COVID-19), often featuring fever and cough symptoms, is primarily addressed with this treatment combination strategy. Maxing Shigan Decoction, a tried and true herbal formula, is a standard treatment for the obstructing lung syndrome caused by phlegm-heat. Nucleic Acid Detection The body's response to sweating, evidenced by dyspnea, may be linked to the presence of excessive pathogenic heat in the lungs. Patients with mild symptoms might experience a combination of cough, asthma, and forehead sweating, whereas those in a critical condition may develop widespread perspiration, particularly on their front chest. Modern medical theory associates the stated condition with an infection centered within the lung. Rather than delving into disease origins, 'mild fever' highlights a constellation of symptoms. The absence of a light symptom does not negate the severity of heat syndrome, but rather implies significant thermal injury and inflammation. Xiao Chaihu Decoction and Maxing Shigan Decoction, when used together, manifest these indications. The treatment is suitable for the management of viral pneumonia, bronchopneumonia, lobar pneumonia, mycoplasma pneumonia, COVID-19 infection, measles complicated by pneumonia, SARS, avian influenza, H1N1 influenza, exacerbations of chronic obstructive pulmonary disease, pertussis, and other influenza and pneumonia-related illnesses. Bitter mouth, dry throat, vertigo, lack of appetite, irritability, vomiting, and chest and hypochondrium discomfort or fullness are among the conditions treatable by this method. Immuno-related genes This treatment can also address alternating episodes of chills and fever, along with various grades of fever, as well as chest tightness, coughing, asthma, expectoration, dryness of the mouth, a desire for cool drinks, agitation, sweating, yellow urine, hard stools, a red tongue, yellow or white fur, and a powerful, floating pulse, especially perceptible in the right radial pulse.
Zhang Zhong-jing, a prominent physician of the Han dynasty, described Zhenwu Decoction in his Treatise on Febrile Diseases. Zhenwu Decoction, primarily treating edema of yang-deficiency origin, accomplishes this through its warming effect on yang, its transformation of Qi, and its encouragement of urination. The investigation of severe and critical cases, combined with the study of pathophysiological mechanisms, confirms that Zhenwu Decoction in Treatise on Febrile Diseases outlines the clinical manifestation and therapeutic procedure of acute heart failure. Misdiagnoses and incorrect therapeutic approaches could be related to the syndrome this formula is designed to treat. The challenge in differentiating cardiogenic dyspnea from pulmonary dyspnea may result in the inappropriate use of high Ephedrae Herba dosages for promoting sweating. This incorrect usage could potentially lead to acute complications including heart failure exacerbation, electrolyte disturbances, and pulmonary infections. The syndrome that Zhenwu Decoction targets serves as a testament to the limited knowledge ancient physicians possessed regarding the treatment of acute heart failure. Trembling and shivering, a potential clinical indicator of heart failure, an advanced form of trembling and shaking, may be treated with Linggui Zhugan Decoction. From a medical perspective, Zhenwu Decoction is indicated for the treatment of acute or chronic heart failure, cardiorenal syndrome, and instances of diuretic resistance. For cases of whole heart failure, acute heart failure, heart failure with reduced ejection fraction, and heart failure characterized by the syndrome of cold and dampness, this decoction is a particularly effective treatment. Along with its other purposes, it can be employed for treating both type and type cardiorenal syndrome. The symptoms treatable with Zhenwu Decoction include tightness in the chest, rapid heartbeats, lower limb swelling, difficulties with urination (increased or decreased), a fear of cold, a tongue that appears pale with tooth marks, a white and slippery tongue coating, and a pulse that may be slow or deep in character. The pharmacological mechanism of Zhenwu Decoction for heart failure involves the promotion of urination, the expansion of blood vessels, and the strengthening of the heart, as viewed through a modern medical lens. Within this formula, Aconiti Lateralis Radix Praparata is the principal herb, recommending a dosage between 30 and 60 grams. Despite its potential benefits, excessive amounts of Aconiti Lateralis Radix Praparata may induce arrhythmia, necessitating careful consideration before usage. Recovery from the ailment can be supported by the use of Zhenwu Decoction, Shenqi Pills, Renshen Decoction, Wuling Powder, and Fangji Huangqi Decoction. These all contribute to the strengthening of the spleen, supplementing Qi, and promoting Yang warmth, and increasing urination. Yang reinforcement therapy remained as the last resort for severe cases, complicated by a lack of specific medical conditions and an ambiguous clinical history, requiring impartial assessment.
Zhang Zhong-jing's Essentials from the Golden Cabinet (Jin Kui Yao Lue), compiled during the Han dynasty, first described Huangtu Decoction's application in treating distal bleeding. The primary treatment addresses the syndrome of uncontrolled blood sugar due to spleen-yang deficiency. Extensive distal bleeding includes not only traditional upper gastrointestinal bleeding—such as peptic ulcer disease, gastrointestinal tumors, stomach lesions, vascular malformations, esophageal and gastric varices, and pancreatic/biliary injuries—but also diverse anorectal conditions like colon and rectal cancers, polyps, hemorrhoids, fissures, alongside other bleeding sources including nosebleeds, low blood counts, irregular menstrual bleeding, threatened pregnancies, and undiagnosed urinary blood. Distal bleeding frequently shows a comorbidity with a failure of the body to retain heat and appropriate fluids within the interior, including such symptoms as nocturia, enuresis, rhinorrhea, sweating, cold tears, and leucorrhea, along with substantial gastrointestinal bleeding triggered by anti-platelet and anticoagulant medications, unidentifiable positive fecal occult blood tests, and various modern clinical complications. Indications for Huangtu Decoction, a traditional Chinese medicine remedy, are not limited to lower blood, pre-blood defecation, distant blood, hematemesis, epistaxis, and other conditions, but additionally include three distinct clinical patterns: bleeding, deficiency symptoms, and stagnant heat.